Sanford is a town in York County, Maine, United States. The population was 20,806 in the 2000 census, the highest of the York County towns, and the 8th largest in the state. Situated on the Mousam River, Sanford includes the village of Springvale. The town features many lakes in wooded areas which attract campers. Sanford is part of the Portland–South Portland–Biddeford, Maine Metropolitan Statistical Area.