Womelsdorf, named after John Womelsdorf, is a borough in Berks County, Pennsylvania, United States. The population was 2,599 at the 2000 census. The main thoroughfares through Womelsdorf is High Street which runs east-west through the borough and Route 419 which runs north-south. Route 422 is located on the northern edge of town. A Pennsylvania state historic site, the Conrad Weiser Homestead, is located in Womelsdorf. This site interprets the life of Conrad Weiser, a well-known 18th century German immigrant who played a major role in the history of colonial Pennsylvania.