Mineola is a city in Wood County, Texas, United States. It lies at the junction of U.S. highways 69 and 80, eighty miles east of Dallas in southwestern Wood County. The population was 4,550 at the 2000 census. However, 2008 estimates put the population at 5,169. William Jesse McDonald, one of the four best known captains of the Texas Rangers, was a storekeeper and then Wood County deputy sheriff in Mineola in the late 19th century.