Anadarko is a city in Caddo County, Oklahoma, United States. The population was 6,645 at the 2000 census. It is the county seat of Caddo County. The town is the home of the Native American drum group Cozad Singers. It is the birthplace of writer Jim Thompson, the Comanche-Kiowa artist Blackbear Bosin, and major league baseball pitcher Cal McLish.