Burkeville is a town in Nottoway County, Virginia, United States. The population was 489 at the 2000 census. The source of the town name is disputed. The town is located on the crossroads of U.S. Routes 360 and 460. Burkeville has a stone quarry, a Tyson Chicken plant, and the Piedmont Geriatric Hospital. There is also a camp retreat for the blind.