Harpersville is a town in Shelby County, Alabama, United States. At the 2000 census the population was 1,620. The small town is growing due to the growth of big business on Highway 280. The town contains Morgan Creek Winery, Baker's Christmas Tree Farm, a historic graveyard, Sunbelt sod farm, a drive in movie theater, numerous cotton fields, a public park, two private schools, and numerous subdivisions. The current mayor, Theoangelo Perkins, is the first African American mayor in Shelby County.