Rensselaer is a city in Rensselaer County, New York, U.S. , and is located on the Hudson River directly opposite Albany. As of the 2000 census, the city population was 7,761; in 1920, it was 10,832. The name is from Kiliaen van Rensselaer, the original landowner of the region in New Netherland. Rensselaer is on the west border of the county. Earliest settlement occurred as early as 1628. The city has a rich industrial history stretching back to the 1800s, when it became a major railroad hub, a distinction which it maintains as the location of the 14th busiest Amtrak station. It was one of the earliest locations of the dye industry in the United States, and the first American location for the production of Aspirin.