Dubois is a city in Clark County, Idaho, United States. The population was 647 at the 2000 census. The city is the county seat of Clark County. The city was named for U.S. Senator Fred Dubois. Six miles (10 km) north of town is the U.S. Sheep Experiment Station, the county's second largest employer. The station studies sheep breeds to support U.S. sheep farmers. Dubois is near the Caribou-Targhee National Forest, which calls one of its administrative units the Dubois ranger district.