Cambridge is a city in Isanti County, Minnesota, United States, located at the junction of Minnesota State Highways 65 and 95. The population was 5,520 at the 2000 census. It is the county seat of Isanti County. It is located along the Rum River and the BNSF Railway. Cambridge is notable for having the highest percentage of Swedish Americans of any city in the United States with a population of over 5,000 people.