Owensboro is the third-largest city in the U.S. state of Kentucky and the county seat of Daviess County. It is located on U.S. Route 60 about 32 miles southeast of Evansville, Indiana and is the principal city of the Owensboro, Kentucky Metropolitan Statistical Area. The population was 55,512 at the 2008 U.S. Census Estimate. The city was named after Colonel Abraham Owen. Owensboro is the second-largest city in the Tri-State region of Illinois, Indiana, and Kentucky after Evansville, Indiana.