East Fultonham is an unincorporated community in central Newton Township, Muskingum County, Ohio, United States. Although it is unincorporated, it has a post office, with the ZIP code of 43735. It is located along U.S. Route 22 a short distance east of the village of Fultonham. It is noted as the birthplace of U.S. Vice President Thomas A. Hendricks. A private lake and beach club, Lake Isabella, has been a popular summer destination since the 1950s. East Fultonham was originally named Axline, Ohio. Early industries included brickmaking, milling, railroading, and limestone quarrying, with the Columbia Cement Company as the largest employer in the area until it closed in the 1980s.