Sayreville is a borough located on the Raritan River, near Raritan Bay in Middlesex County, New Jersey. As of the United States 2000 Census, the borough population was 40,377. It was ranked 47th by Money Magazine for the best places to live in 2007 Sayreville was originally incorporated as a township on April 6, 1876, from portions of South Amboy Township. On April 2, 1919, the borough was reincorporated as the Borough of Sayreville, based on the results of a referendum held on April 29, 1919.