¶2 Roderick L. Mitchell, a California state prisoner, appeals pro se from the district court’s judgment dismissing his 42 U.S.C. § 1983 action alleging deliberate indifference to his serious medical needs. We have jurisdiction under 28 U.S.C. § 1291. We review de novo a district court’s dismissal under Federal Rule of Civil Procedure 12(b)(6), Hebbe v. Pliler, 627 F.3d *709 338, 341 (9th Cir.2010), and for an abuse of discretion a dismissal without leave to amend, Halet v. Wend Inv. Co., 672 F.2d 1305, 1310 (9th Cir.1982). We affirm.
¶3 The district court properly dismissed the action because Mitchell failed to state sufficient facts to show that defendants acted with deliberate indifference to his carpal tunnel condition. See Toguchi v. Chung, 391 F.3d 1051, 1058 (9th Cir.2004) (a prison official acts with deliberate indifference only if he or she knows of and disregards an excessive risk to the prisoner’s health and safety, and a difference in medical opinion is insufficient to establish deliberate indifference).
¶4 The district court did not abuse its discretion by dismissing Mitchell’s complaint without leave to amend because amendment would have been futile. See Lopez v. Smith, 203 F.3d 1122, 1130 (9th Cir.2000) (en banc) (a district court need not grant ’leave to amend if the defects of the complaint cannot be cured).
¶5 Mitchell’s remaining contentions are unpersuasive.
¶6 AFFIRMED.