Cristal C. Brisco (née Clark; born 1981) is an American lawyer who has served as a United States district judge of the United States District Court for the Northern District of Indiana since 2024. She previously served as a judge of the St. Joseph County Superior Court from 2021 to 2024.

- Gender
- Female
- Race
- African American
Prior employment
- St. Joseph County [Indiana] Superior Court, Civil DivisionJudge · 2021–2024
- Indiana Commercial CourtJudge · 2022–2024
- Indiana Circuit Court, Sixtieth Judicial CircuitMagistrate judge · 2018–2021
- The Corporation of St. Mary's College–Notre DameGeneral counsel · 2017–2018
- South Bend, IndianaCorporation counsel · 2013–2017
- Private practice, South Bend, Indiana2006–2013
Appointments
2024–present · Appointed by Joseph R. Biden (Democratic)
Education
- Notre Dame Law SchoolJ.D. · 2006
- Valparaiso UniversityB.A. · 2002