Margaret Rose Guzman (born 1960) is an American attorney serving as a United States District Judge of the United States District Court for the District of Massachusetts. She previously served as a judge of the Ayer District Court in Middlesex County, Massachusetts.

- Gender
- Female
- Race
- Hispanic/White
Prior employment
First justice · 2017–2023
Trial advocacy workshop instructor · 2019, 2020, 2022- National Judicial CollegeGeneral jurisdiction/core skills faculty · 2020, 2021
- Commonwealth of Massachusetts Trial CourtAssociate justice of the district court · 2009–2017
- Private practice, Worcester, Massachusetts2005–2009
Criminal Justice Act Panel attorney · 2007–2009- Committee for Public Counsel Services, Worcester, MassachusettsTrial attorney · 1992–2005
Appointments
2023–present · Appointed by Joseph R. Biden (Democratic)
Education
J.D. · 1992- Clark UniversityB.A. · 1989