Serena Raquel Murillo (born 1970) is an American lawyer who is serving as a United States district judge of the United States District Court for the Central District of California. She previously served as a judge of the Los Angeles County Superior Court.

- Gender
- Female
- Race
- Hispanic
Prior employment
- University of California Gould School of LawLecturer · 2022–present
- Superior Court of California, County of Los AngelesJudge · 2015–2024
- University of California, Irvine School of LawLecturer · 2022
- California Court of Appeal, Second DistrictAssociate justice pro tem · 2018–2019
- Los Angeles, CaliforniaDeputy district attorney · 1997–2014
- Private practice, Los Angeles, California1997
Appointments
2025–present · Appointed by Joseph R. Biden (Democratic)
Education
- Loyola Law School, Los Angeles, CaliforniaJ.D. · 1996
- Loyola Marymount Universityjd · 1996
- University of California, San DiegoB.A. · 1993
- University of California-San Diegoba · 1993