Port Orange is a city in Volusia County, Florida, United States. In 2006, the U.S. Census Bureau estimated the city's population as 52,793. The city is part of the Deltona-Daytona Beach-Ormond Beach, Florida Metropolitan Statistical Area; the metropolitan area's 2006 population was estimated at 496,575. Port Orange is also a principal city in the Fun Coast region of the state of Florida.