Kaukauna is a city in Outagamie County, Wisconsin, United States, on the Fox River, approximately 100 miles (161 km) north of Milwaukee, with a population of 12,983. It is a part of the Appleton, Wisconsin Metropolitan Statistical Area, which is included in the Appleton-Oshkosh-Neenah, Wisconsin Combined Statistical Area with a combined population of around 350,000. It is considered the easternmost of the Fox Cities.